Please kindly take note of the following important changes for the ethics application submitted to the UMMC-Medical Research Ethics Committee (UMMC-MREC).
1. Form for Comments by the Head of Department / Dean / Director
Effective date: 1st July 2022
2. Implementation of Health Research Ethics Certification
Effective date: 27th August 2022
See more on our FAQ (Q16)
WELCOME TO UMMC-MREC
Overview of UMMC-MREC
University of Malaya Medical Centre-Medical Research Ethics Committee (UMMC-MREC) was formerly known as Medical Ethics Subcommittee (MESC) established under the Medical Advisory Committee of University Hospital in 1970s. In 2016, the committee was renamed as Medical Research Ethics Committee (MREC). This ethics committee (or institutional review board) is an independent body of medical/scientific professionals and non-medical/non-scientific members that reviews, approves and provides continuing review of human research/trial protocols and amendments, and of the methods and materials to be used in obtaining and documenting consent of the human research subjects.
The Authority of the MREC
The MREC has the authority to approve a proposed study, require modification of the study or disapprove the study. The MREC is also authorized to monitor studies and may suspend or terminate any previously approved study, and approve or disapprove protocol amendments to an approved study. In accordance with ICH-GCP guidelines, the following must be promptly reported to the MREC:
Changes to the approved protocol (to reduce/ eliminate risk to subjects),
All serious adverse events and serious adverse reactions,
New information that may adversely affect the safety of subjects or conduct of the trial,
When a study is discontinued prematurely, and
When a study is completed.
What is Research Ethics and its importance?
Research ethics govern the standards of conduct for scientific researchers. It is important to adhere to ethical principles in order to protect the dignity, rights, and welfare of research participants.
Principles and benchmarks for ethical research are summarised as below:
Respect for persons
Autonomy - Informed consent
Favourable risk-benefit ratio
Fair participant selection
UMMC-MREC Committee Members
The committee consists of medical/scientific professionals and non-medical/non-scientific/public members that review, approve, and provide a continuing review of human research/trial protocols and amendments, and of the methods and materials to be used in obtaining and documenting consent of the human research subjects.
The MREC answers to the Board of Directors, UMMC but is independent in its decision-making. The decisions of the MREC are also informed to the Medical Advisory Committee (body of clinical consultants) of UMMC.
UMMC-MREC Secretariat Office (Jawatankuasa Etika Penyelidikan Perubatan),
Level 2, Kompleks Pendidikan Sains Kejururawatan,
University of Malaya Medical Centre,
Lembah Pantai, 59100
Kuala Lumpur, Malaysia.
03-7949 3209 (Mdm. Ros) / 2251 (Mr. Izanie) / 8473 (Ms. Grazele)/ 4656 (Dr. Phang)